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Synovial fluid is actually quite viscous and does not have the same consistency as plasma. The reason for its thicker consistency is to provide cushion and reduce friction between the articular cartilage of synovial joints during movement.

Urinalysis & Other Body Fluids

All of the statements below about synovial fluid are true EXCEPT:

A.

arthrocentesis is performed as a means to evaluate arthritis and other joint disorders

B.

synovial fluid is present only in movable joints

C.

joint fluid resembles plasma in viscosity

D.

joint fluid has approximately the same glucose as plasma

G6PD deficiency causes an increased suseptibility to the oxidation of hemoglobin, which in turn, causes the precipitation of hemoglobin inside of the red blood cell.

Which one of the following conditions is associated with glucose-6-phosphate dehydrogenase (G6PD) deficiency?

A.

Microcytic red cells

B.

Precipitation of hemoglobin

C.

Faulty heme synthesis

D.

Hemoglobins with low oxygen affinities

Which of the following tubes produces a serum sample?

Question options:

A.

green

B.

pink

C.

tiger (red-gray)

D.

blue

Most researchers believe that the small size and increased density of LDL molecules found in atherogenic dyslipidemia enable the molecules to more easily invade the endothelium and arterial wall of vessels.

Why are small dense LDL molecules more atherogenic?

A.

Small dense LDL molecules contain less cholesterol and phospholipid

B.

Small dense LDL molecules increase the concentration of HDL-C in the blood

C.

Small dense LDL molecules increase the concentration of adoponectin and inflammatory cytokines

D.

Small dense LDL molecules have greater mobility in the endothelium and arterial wall

This drawing depicts beta thalassemia minor B+/B. In Beta thalassemia minor B+/B, one beta gene locus is partially deleted or inactive.

Hematology

This drawing depicts which beta chain genotype ?

A.

Beta thalassemia minor

B.

Beta thalassemia intermedia

C.

Beta thalassemia major

D.

Delta-beta thalassemia minor

Lipids tend to form a "maltese cross" pattern when viewed in polarized light, which helps to differentiate them from other urine microscopic components.

Substances found in urinary sediment that are more easily distinguished by use of polarized microscope are:

A.

WBC

B.

RBC

C.

Casts

D.

Lipids

E.

Crystals

Which of the following Rh antigens is found the highest frequency in the Caucasian population:

A.

C

B.

E

C.

c

D.

e

A test with high specificity accurately detects the absence of disease. The more specific a test is, the fewer false-positive results will occur. A test with high sensitivity accurately identifies the presence of disease. The more sensitive a test, the fewer false-negative results it produces. In the case stated in this question, the immunoassay has high specificity, so it has few false-positives and will accurately detect those individuals who do not have the disease or condition that is being tested for. However, the test has low sensitivity, so it may not identify all individuals who actually have the disease; it may produce many false-negative results.

The accuracy of an immunoassay is its ability to discriminate between results that are true positives and results that are true negatives. Two parameters of test accuracy are specificity and sensitivity. Which of these statements apply to an immunoassay with high specificity, but low sensitivity?

A.

Accurately identifies the presence of disease

B.

Accurately identifies the absence of disease

C.

Has few false-positives

D.

Has few false-negatives

1. B

2. D

3. A

4. C

Red to Brown Urine: porphobilinogen, hematuria, myoglobinuria, etc.

Green: Food colorings; Increased carotene in the diet;

Pseudomonas aeruginosa infection

Yellow: bilirubin, bile pigments

White: phosphates, other crytals

Match urine color with substance that might have been responsible:

1. Phosphates

2. Bilirubin

3. Pseudomonas

4. Porphobilinogen

A.

Blue to green

B.

White

C.

Red to brown

D.

Yellow

In order to perform a venipuncture on a newly admitted hospital patient, a phlebotomist needs to

A.

Ask for the patients' written permission to perform the procedure.

B.

Verfity that the patient has specifically name the drawing of blood in the admission process.

C.

Realize that an admitted hospital patient has given implied consent to routine procedures such as phlebotomy.

D.

Verify with the patient's primary care provider that phlebotomy is covered as a routine procedure.

Clostridium difficile is a gram-positive, anaerobic, spore-forming bacillus that produces a strong toxin. C difficile is a common cause of antibiotic-associated diarrhea and pseudomembranous colitis.

Microbiology

A recto-sigmoidoscopy revealed pseudomembranes in a patient with severe diarrhea following prolonged treatment with ampicillin. Which of the following organisms is MOST likely to be isolated?

A.

Bacteroides fragilis

B.

Clostridium botulinum

C.

Clostridium difficile

D.

Fusobacterium nucleatum

E.

Klebsiella oxytoca

Match each of the descriptions with the appropriate magnification:

1. Color, Rouleau, Overall Slide Quality, Cell Distribution

2. Platelet estimates RBC-platelet-WBC morphology WBC differential RBC inclusions

3. Select area to examine, WBC estimate

A.

40X (Dry)

B.

10X

C.

100X (Oil)

Anti-A, anti-P, anti-Leb, and anti-M all react best at 4o C as they are predominantly IgM antibodies. Other antibody group choices above include IgG antibodies such as anti-K, anti-s, anti-S, and anti-Fya, anti-Lub, etc. which react best at 37o C.

Which of the following groups of antibodies generally reacts most strongly at 4o C:

A.

Anti-A, Anti-P1 , Anti-Leb , Anti-M

B.

Anti-B, Anti-K, Anti-Lua , Anti-Fya

C.

Anti-H, Anti-S, Anti-Jkb , Anti-Leb

D.

Anti-A, Anti-K, Anti-Lub , Anti-s

Which of the following organizations now provides the certification exam for laboratory professionals?

A.

National Credentialing Agency (NCA)

B.

American Society for Clinical Laboratory Scientists (ASCLS)

C.

Board of Registry (BOR)

D.

National Accrediting Agency for Clinical Laboratory Sciences (NAACLS)

Hb S migrates with D in alkaline and alone in acid electrophoresis.

The gel electrophoresis pattern for hemoglobin S shows which of the following migration patterns?

A.

Hb S migrates alone in alkaline and D in acid electrophoresis.

B.

Hb S migrates with D in alkaline and A in acid electrophoresis.

C.

Hb S migrates with D in alkaline and alone in acid electrophoresis.

D.

Hb S migrates with A in alkaline and D in acid electrophoresis.