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An oral chelating agent used in the treatment of rheumatoid arthritis is:

A.

Allopurinol

B.

Sulphinpyrazone

C.

Indomethacin

D.

Penicillamine

E.

Methotrexate

A patient purchasing sublingual nitroglycerin tablets should be told to store the medication:

A.

in the refrigerator

B.

in a plastic vial with a childproof cap

C.

with the original cotton

D.

in an amber glass bottle with a metal cap

E.

in a warm, dry place

The method of ionization of mass spectrometry which results in well-established diagnostic fragmentation patterns that are useful in the identification of compounds of unknown structure is called:

A.

atmospheric pressure chemical ionization (APCI)

B.

chemical ionization (CI)

C.

electron impact (EI) ionization

D.

electrospray ionization (ESI)

E.

fast atom bombardment (FAB. ionization

F.

Pharmacy Practice

Use of estrogen in osteoporosis:

I- Estrogen enhance calcium retention and retard bone loss

II- Estrogen is useful in treat osteoporosis associated to menopause

III- Estrogen is not effective at increasing bone mass that has already been lost.

A.

I only

B.

III only

C.

I and II only

D.

II and III only

E.

All are correct

The pharmacist fills a prescription for sumatriptan 100 mg tablets for a migraine patient. Appropriate information to provide to the patient includes which of the following?

A.

If the sumatriptan does not relieve the headache within four hours, ergotamine may be used.

B.

If no relief is achieved in two hours, sumatriptan may be repeated.

C.

If the headache is relieved but another headache occurs eight hours later, sumatriptan may be used for the second headache.

D.

The maximum dosage in any 24 hour period is six tablets.

E.

If relief is not achieved, no other medication can be used for 24 hours.

Approximately 50% of dicloxacillin is excreted unchanged in the urine. If the normal dosage schedule for dicloxacillin is 125 mg q6h, a patient with renal function 20% of normal should receive:

A.

25 mg q6h

B.

31.25 mg q6h

C.

62.5 mg q6h

D.

75 mg q6h

E.

125 mg q12h

All of the following drugs will increase the heart rate directly or by reflex when injected intravenously into a young healthy adult, EXCEPT:

A.

isoproterenol

B.

histamine

C.

phentolamine

D.

phenylephrine

E.

atropine

The following prescription is received in a community pharmacy:

Losec® 20 mg

S: Take 1 tab BID

M: 2 weeks

Which of the following is correct labelling for this prescription?

A.

Take one tablet twice weekly (28 tablets).

B.

Take one tablet twice weekly (4 tablets).

C.

Take two tablets twice daily (56 tablets).

D.

Take one tablet twice daily (28 tablets).

E.

Take one tablet twice daily (14 tablets)

The Latin abbreviation for "before meals" is:

A.

ac

B.

aa

C.

pc

D.

ic

E.

cc

Reasons for using coatings on tablets include all of the following, EXCEPT:

A.

to mask the taste of the drug

B.

to mask the odor of the drug

C.

to improve the appearance of the tablet

D.

to increase the drug's release rate

E.

to protect the drug from stomach acid