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The membranes of ion selective electrodes will determine which analyte is measured by the electrode.

Chemistry

The selectivity of an ion-selective electrode is determined by the:

A.

properties of the membrane used

B.

solution used to fill the electrode

C.

magnitude of the potential across the membrane internal reference electrode

D.

type of glass used in electrode

Urinalysis & Other Body Fluids

Match the following urine chemical reagent strip test pads to the disease or disorder that would most likely cause a positive test result.

1. Ketones

2. Blood

3. Bilirubin

4. Nitrites

A.

Renal calculi

B.

Urinary tract infection

C.

Diabetes mellitus

D.

Hepatitis/cirrhosis

Stuart Prower factor, or factor X, would cause abnormal PT, aPTT, and dRVVT test results as factor X is part of the common coagulation pathway and therefore measured in both the PT and aPTT test. In the dRVVT test, factor X is directly activated in the test principle; therefore an abnormal result would be expected in this test as well if there was a deficiency in factor X.

What tests will be abnormal in a patient with Stuart-Prower Factor deficiency?

A.

Prothrombin Time (PT)

B.

Activated Partial Thromboplastin Time (APTT)

C.

Russel Viper Venom Test (dRVVT)

D.

a & b

E.

a & b & c

There are many causes of CSF lymphocytosis. Lymphocytosis is seen in viral, fungal, and tuberculous infections, although a predominance of neutrophils may be present in the early stages of these infections. Lumbar puncture to obtain CSF samples is often contraindicated in those with a suspected brain abscess.

CSF lymphocytosis is associated with all of the following except:

A.

Cerebral abscess

B.

Viral meningitis

C.

Chronic fungal meningitis

D.

Chronic tuberculous meningitis

Mrs. Jones, a diabetic, is admitted to the hospital on November 25th. It appears that she has had an AMI but did not feel the severe chest pain because of diabetic neuropathy. She has not felt well since November 20th and her physician believes she possibly had an AMI on November 20th.

Assuming that the infarct was uncomplicated, which of the following cardiac biomarkers would most likely still be elevated and would assist in an AMI diagnosis?

A.

Myoglobin

B.

Creatine kinase MB (CK-MB)

C.

Cardiac troponin I (cTnI) or cardiac troponin T (cTnT)

Valine substitutes for glutamic acid in the Beta 6 position to produce HbS.

To produce hemoglobin S, glutamic acid that is normally present in the sixth position on the beta globin chain is substituted with which of the following?

A.

Cystine

B.

Guanine

C.

Thyamine

D.

Valine

Provide the equivalent measurement for 75 milligrams.

Question options:

A.

75,000 micrograms

B.

750 micrograms

C.

750,000

D.

7500 micrograms

The end of the initial phase of HH treatment is considered when the serum ferritin decreases to between 20 and 50 ng/mL.

What is a typical finding for determining the endpoint for the initial or iron-depletion phase of treatment for hereditary hemochromatosis (HH)?

A.

The serum ferritin decreases to between 20 and 50 ng/mL

B.

The hepatic iron index returns to normal

C.

The transferrin saturation drops below 20%

D.

The serum iron falls to below 35 g/dL.

In Rouleaux, red blood cells appear as stacked coins - formation occurs as the result of elevated globulins or fibrinogen.

The RBCs indicated by the arrows in this illustration are the result of:

A.

Over drying of blood smear

B.

Rouleaux formation

C.

Cold agglutinins

D.

Sickle cell anemia

Acute hemolytic transfusion reactions are most commonly due to ABO-incompatible blood being transfused to a recipient with naturally occurring ABO alloantibodies (anti-A, anti-B, anti A,B).

Acute intravascular hemolysis as the result of a blood transfusion is most often associated with which of the following causes?

A.

Transfusion of ABO incompatible red cells

B.

Allergies

C.

Passively transfused antibodies to HLA antigens

D.

Transfusion-associated graft-versus-host disease

HbsAg is positive in acute and chronic Hepatitis B infections, since the antigen is found on the actual surface of the virus. HbeAg is present in the blood when the hepatitis B viruses are replicating, indicating an active infection. Anti-Hbc IgM is present due to the immune response to the presence of the hepatitis core antigen and indicates an acute infection. Anti-HBs is generally interpreted as indicating recovery and immunity from hepatitis B virus infection, according to the CDC.

Given the following results, what is the immune status of the patient?

HbsAg: positive

HbeAg: positive

Anti-HBc IgM: positive

Anti-HBs: negative

A.

acute infection

B.

chronic infection

C.

immunization

D.

susceptible

Although cysteine-blood agar was traditionally used, F. tularensis will also grow on commercially available Thayer-Martin and chocolate agar which have been enriched with supplemental nutrients.

Which of the following media would you use to isolate Francisella tularensis:

A.

Sheep-blood agar

B.

Lowenstein-Jensen media

C.

Bordet-Gengou media

D.

Cysteine-blood agar

Which specimen should be collected last?

Question options:

A.

Specimen requiring special handling

B.

Clotted specimen

C.

Fasting specimen

D.

STAT specimen

Neutrophils reside in the peripheral circulation for only 7-8 hours ( approx. 7.5 hours) before entering the tissues and body cavities. This process is called diapedesis.

Hematology

How long are healthy neutrophils expected to reside in the peripheral blood of an adult?

A.

3 days

B.

1 day

C.

7-8 hours

D.

12-14 hours

Free T4 is affected the least by changes in plasma proteins during pregnancy.

Which of the following thyroid function assays is affected least by pregnancy:

A.

Total T3

B.

Total T4

C.

Free T4